A Bach2 link between pre-B cell receptor checkpoint and pre-B cell ALL.
نویسندگان
چکیده
Bach2 is a transcription factor required for affinity maturation of B cells. A recent study reveals, quite unexpectedly, that Bach2 also plays a key role in the pre-B cell receptor checkpoint and functions as a tumor suppressor in pre-B cell acute lymphocytic leukemia.
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عنوان ژورنال:
- Cancer cell
دوره 24 3 شماره
صفحات -
تاریخ انتشار 2013